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There are no or limited amount of data from the use of colecalciferol in pregnant women. Studies in animals have shown reproductive toxicity. However, the risks to the mother and fetus from untreated hypoparathyroidism or hypophosphatemia may be greater than those resulting from administration of vitamin D analogs. Large doses of vitamin D analogs should not be administered to nursing women.
The recommended daily intake for pregnant women is 400 IU, however, in women who are considered to be vitamin D deficient a higher dose may be required. During pregnancy women should follow the advice of their medical practitioner as their requirements may vary depending on the severity of their disease and their response to treatment.
During lactation, small and probably unimportant amounts of maternal circulating vitamin D and its metabolites are distributed into breast milk. Evidence from randomized controlled studies and observational data indicate that increased maternal intake of vitamin D has no effect on neonatal excessive.
